Ursodiol

Generic name: Ursodiol

Drug class: Gallstone solubilizing agents

Dosage forms: Capsule, Tablet

Root of administration: Oral

Dose: 200, 250, 300, 400, 500 mg

Mechanism of action: The mechanism of action of ursodiol involves several effects on the liver and bile production.

Drug usage cases: Ursodiol capsules are used to dissolve small gallstones that cannot be removed with surgery, or to prevent gallstones that may occur during rapid weight loss. Ursodiol will not dissolve calcified gallstones. Ursodiol tablets are used to treat primary biliary cirrhosis, an autoimmune disorder that causes progressive destruction of the bile ducts in your liver.

Drug contra indications: You should not use ursodiol if you are allergic to it, or if you have an obstruction in your liver or gallbladder. Tell your doctor if:

you have been coughing up blood; or you have gained weight rapidly, especially in your face and midsection. Not approved for use by anyone younger than 18 years old.

Side effects: Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Ursodiol may cause serious side effects. Call your doctor at once if you have:

pain or burning when you urinate; stomach pain or discomfort, constipation, vomiting; liver problems–nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or signs of a new infection–sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, skin sores, trouble swallowing.

Warnings: Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Use during pregnancy or breastfeeding: Tell your doctor if you are pregnant or breastfeeding