Havrix

Generic name: hepatitis A adult vaccine [ HEP-a-TYE-tis ]
Brand names: Havrix, Vaqta

Drug Class: Vaccine, Inactivated

Dosage Form: Injectable Solution

Route of Administration: Intramuscular

Dose:

• Children: Typically 0.5 mL
• Adults: Typically 1 mL

Mechanism of Action: Havrix is a hepatitis A vaccine containing inactivated hepatitis A virus. It stimulates the immune system to produce antibodies against hepatitis A, providing immunity to the virus.

Drug Usage Cases: Havrix is used to prevent hepatitis A virus infection. It is administered to children and adults, particularly those at risk of exposure or in regions where hepatitis A is common.

Drug Contraindications: Contraindicated in patients with known hypersensitivity to the vaccine or any component of the formulation, including neomycin and latex (if used in the vial stopper).

Side Effects: Common side effects include pain at the injection site, headache, and fatigue. Serious side effects are rare but can include severe allergic reactions and anaphylaxis.

Warnings: People with compromised immune systems or those receiving immunosuppressive therapy may have a reduced response to the vaccine. It should be used with caution in patients with bleeding disorders.

Use During Pregnancy or Breastfeeding: Havrix is classified under FDA Pregnancy Category C. It should be used during pregnancy only if clearly needed and if the potential benefit justifies the potential risk. There is limited information on its excretion in human milk; caution should be exercised when administered to a nursing mother.