Allzital

Generic name: acetaminophen and butalbital

Drug class: Analgesic combinations

Dosage form: Tablet

Route of administration: Oral

Dose: 25 mg butalbital and 325 mg acetaminophen per tablet; typically, 2 tablets every 4 hours as needed, not exceeding 12 tablets in 24 hours. Extended and repeated use is not recommended due to potential for physical dependence.

Mechanism of action: Butalbital is a barbiturate that relaxes muscle contractions involved in tension headaches. Acetaminophen is an analgesic and antipyretic that reduces pain and fever.

Drug usage cases:

• Acute treatment of tension headaches

Drug contraindications:

• Hypersensitivity to acetaminophen or butalbital
• Porphyria
• Severe liver disease
• History of drug or alcohol addiction
• Concurrent use with other medications containing acetaminophen

Side effects:

• Drowsiness
• Dizziness
• Lightheadedness
• Shortness of breath
• Nausea
• Vomiting
• Abdominal pain
• Intoxicated feeling
• Headache
• Shaky feeling
• Tingling
• Agitation
• Fainting
• Fatigue
• Heavy eyelids
• High energy
• Hot spells
• Numbness
• Sluggishness
• Seizure
• Dry mouth
• Hyperhidrosis
• Difficulty swallowing
• Heartburn
• Flatulence
• Constipation
• Tachycardia
• Leg pain
• Muscle fatigue
• Diuresis
• Pruritus
• Fever
• Earache
• Nasal congestion
• Tinnitus
• Euphoria
• Allergic reactions
• Skin redness or rash that spreads and causes blistering and peeling

Warnings:

• Risk of severe liver damage with acetaminophen overdose
• Potential for habit formation and physical dependence with butalbital
• Risk of severe skin reactions, including toxic epidermal necrolysis and erythema multiforme
• May cause drowsiness; avoid driving or operating heavy machinery
• Alcohol use may increase the risk of liver damage
• Use caution in patients with a history of drug or alcohol addiction
• Not approved for use in individuals under 18 years old

Use during pregnancy or breastfeeding:

It is not known whether Allzital will harm an unborn baby. However, this medicine can cause seizures in a newborn if the mother takes the medicine late in pregnancy. Tell your doctor if you are pregnant or plan to become pregnant. You should not breast-feed while using Allzital.