Cinryze

Generic name: complement C1 esterase inhibitor
Drug class: Hereditary angioedema agents

Dosage form: powder for reconstitution injection
Root of administration: injection
Dose:

• 500 unit/vial
• 2000 IU/vial
• 3000 IU/vial

Mechanism of action: Cinryze is a man-made form of a protein that occurs naturally in the blood stream and helps control swelling in the body. People with a condition called hereditary angioedema do not have enough of this protein. Hereditary angioedema can cause attacks of swelling and symptoms such as stomach problems or trouble breathing.
Drug usage cases: Cinryze is used to prevent attacks of angioedema.
Drug contraindications: You should not use Cinryze if have ever had a life-threatening allergic reaction to complement C1 esterase inhibitor. Tell your doctor if you have ever had:

• a stroke or blood clot
• heart problems
• an “in-dwelling” catheter

Side effects: Call your doctor at once if you have:

• sudden numbness or weakness on one side of the body
• pain, swelling, warmth, or redness in an arm or leg
• sudden severe headache, confusion, problems with vision, speech, or balance
• chest pain while taking deep breaths
• fast heart rate

Warnings: You should not use Cinryze if have ever had a life-threatening allergic reaction to complement C1 esterase inhibitor. Before you receive Cinryze, tell your doctor if you have a history of stroke or blood clot. Do not give this medication to a child without medical advice.

Use during pregnancy or breastfeeding: Tell your doctor if you are pregnant or breast-feeding.