Genvoya

Generic name: cobicistat, elvitegravir, emtricitabine, and tenofovir
Drug class: Antiviral combinations
Dosage form: tablet
Root of administration: oral
Dose: 150, 200, 10mg

Mechanism of action: Genvoya is a tablet containing a combination of cobicistat, elvitegravir, emtricitabine, and tenofovir. Cobicistat reduces the action of enzymes in your liver that break down certain antiviral medicines. This allows the antiviral medicines to be used more safely and effectively at lower doses.
Drug usage cases: Genvoya is used to treat HIV in adults and children who are at least 12 years old and who weigh at least 55 pounds (25 kilograms).
Drug contraindications: Some drugs should not be used with Genvoya. Your treatment plan may change if you also use:

• alfuzosin;
• cisapride;
• oral midazolam, or triazolam;
• rifampin;
• sildenafil (Revatio, for treating pulmonary arterial hypertension);
• St. John’s wort;
• antipsychotic medicine – lurasidone, pimozide;
• cholesterol medication – lomitapide, lovastatin, simvastatin;
• ergot medicine – dihydroergotamine, ergotamine, methylergonovine; or
• seizure medicine – carbamazepine, phenobarbital, phenytoin.

Do not stop using Genvoya without your doctor’s advice. Get your prescription refilled before you run out of medicine completely.
Side effects: Get emergency medical help if you have signs of an allergic reaction to Genvoya:hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• kidney problems – swelling, urinating less, feeling tired or short of breath;
• lactic acidosis – unusual muscle pain, trouble breathing, stomach pain, vomiting, irregular heart rate, dizziness, feeling cold, or feeling very weak or tired; or
• liver problems – nausea, upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Warnings: Genvoya can harm your liver. Call your doctor at once if you have: upper stomach pain, loss of appetite, dark urine, clay-colored stools, or yellowing of your skin or eyes.
Use during pregnancy or breastfeeding: This medicine may not work as well if you take it during pregnancy. Do not start taking the medicine if you are pregnant. Tell your doctor right away if you become pregnant.

If you plan to get pregnant, ask your doctor for another antiviral medicine to use during pregnancy. To prevent HIV in a newborn baby, use all medications to control your infection during pregnancy. Your name may be listed on an antiviral pregnancy registry.

If you do not plan to get pregnant, ask your doctor about using a non-hormonal birth control (condom, diaphragm, cervical cap, or contraceptive sponge) to prevent pregnancy. Genvoya can increase certain side effects when taken with hormonal birth control (pills, injections, implants, skin patches, vaginal rings).

Women with HIV should not breastfeed. The virus can pass to your baby in your breast milk.