Guanfacine

Generic name: guanfacine
Brand names: Intuniv, Tenex
Dosage forms: oral tablet (1 mg; 2 mg), oral tablet, extended release (1 mg; 2 mg; 3 mg; 4 mg)
Drug class: Antiadrenergic agents, centrally acting
Dosage form: tablet
Root of administration: oral
Dose: oral tablet (1 mg; 2 mg), oral tablet, extended release (1 mg; 2 mg; 3 mg; 4 mg)
Mechanism of action: By binding to these receptors, guanfacine reduces the release of norepinephrine (noradrenaline), a neurotransmitter involved in regulating attention, impulse control, and blood pressure. This leads to decreased sympathetic outflow from the central nervous system, resulting in decreased heart rate and blood pressure.
Drug usage cases: Guanfacine is used to treat high blood pressure (hypertension). It is sometimes given with other blood pressure medications. The Intuniv brand of guanfacine is used to treat attention deficit hyperactivity disorder (ADHD). Guanfacine may also be used for purposes not listed in this medication guide.

Drug contraindications: You should not use guanfacine if you are allergic to it.

Intuniv is not approved for use by anyone younger than 6 years old. Guanfacine is not approved for use by anyone younger than 12 years old.

Tell your doctor if you have ever had:

• heart problems, coronary artery disease (clogged arteries)
• a heart rhythm disorder
• a heart attack or stroke
• high or low blood pressure
• liver disease
• kidney disease

Side effects: Guanfacine may cause serious side effects. Call your doctor at once if you have:

• anxiety, nervousness
• hallucinations (especially in children)
• severe drowsiness
• slow heartbeats
• a light-headed feeling, like you might pass out

Warnings: Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.
Use during pregnancy or breastfeeding: It is not known whether guanfacine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breastfeed a baby while you are using this medicine. Ask your doctor about any risks.