Humira
23 June, 2023
Hydrochlorothiazide
23 June, 2023
Hydralazine
Generic name: hydralazine
Brand name: Apresoline
Drug class: Vasodilators
Dosage form: tablet
Root of administration: oral
Dose: 10, 25, 50, 100 mg
Mechanism of action: Hydralazine works by relaxing the smooth muscles in the walls of arterioles, which are small blood vessels. This relaxation occurs through several mechanisms, including the release of nitric oxide (NO) and the inhibition of calcium influx into smooth muscle cells. Nitric oxide causes vasodilation by activating the enzyme guanylate cyclase, which increases cyclic guanosine monophosphate (cGMP) levels. Elevated cGMP levels lead to smooth muscle relaxation and dilation of blood vessels.
Drug usage cases: Guanfacine is used to treat high blood pressure (hypertension). It is sometimes given with other blood pressure medications. The Intuniv brand of guanfacine is used to treat attention deficit hyperactivity disorder (ADHD). Guanfacine may also be used for purposes not listed in this medication guide.
Drug contraindications: You should not use guanfacine if you are allergic to it.
Intuniv is not approved for use by anyone younger than 6 years old. Guanfacine is not approved for use by anyone younger than 12 years old.
Tell your doctor if you have ever had:
- heart problems, coronary artery disease (clogged arteries)
- a heart rhythm disorder
- a heart attack or stroke
- high or low blood pressure
- liver disease
- kidney disease
Side effects: Guanfacine may cause serious side effects. Call your doctor at once if you have:
- anxiety, nervousness
- hallucinations (especially in children)
- severe drowsiness
- slow heartbeats
- a light-headed feeling, like you might pass out
Warnings: Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.
Use during pregnancy or breastfeeding: It is not known whether guanfacine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It may not be safe to breastfeed a baby while you are using this medicine. Ask your doctor about any risks.
