Jeuveau

Generic name: PrabotulinumtoxinA

Drug class: Skeletal muscle relaxants

Dosage form: Injectable Solution

Root of administration: Muscles

Dose: 40 units

Mechanism of action: Jeuveau is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles.

Drug usage cases: Jeuveau is a prescription medicine used to temporarily lessen the appearance of facial wrinkles (frown lines) between the eyebrows) in adults. It is not known if Jeuveau is safe and effective for use in children.

Drug contra indications: You should not be treated with Jeuveau if you are allergic to prabotulinumtoxinA, or if: you have an infection in the area where the medicine will be injected; or

you have ever had an allergic reaction to any product that contains botulinum toxin, such as Botox, Dysport, Myobloc, or Xeomin. To make sure Jeuveau is safe for you, tell your doctor if you have:

other botulinum toxin injections such as Dysport or Myobloc (especially in the last 4 months),

amyotrophic lateral sclerosis (ALS, or “Lou Gehrig’s disease”), myasthenia gravis, Lambert-Eaton syndrome, a side effect after prior use of botulinum toxin, a breathing disorder such as asthma or emphysema, problems with swallowing, facial muscle weakness (droopy eyelids, weak forehead, trouble raising your eyebrows), bleeding problems, heart disease; or surgery (especially on your face). Jeuveau is made from donated human plasma and may contain viruses or other infectious agents. Donated plasma is tested and treated to reduce the risk of contamination, but there is still a small possibility it could transmit disease. Ask your doctor about any possible risk. If you have a planned surgery, tell your surgeon ahead of time about when you last received Jeuveau.

Side effects: Get emergency medical help if you have signs of an allergic reaction to Jeuveau: hives, itching; wheezing, difficult breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat. The botulinum toxin contained in Jeuveau can spread to other body areas beyond where it was injected. This has caused serious life-threatening side effects in some people receiving botulinum toxin injections, even for cosmetic purposes. Call your doctor at once if you have any of these side effects (up to several hours or several weeks after an injection): unusual or severe muscle weakness (especially in a body area that was not injected with the medication); trouble breathing, talking, or swallowing; loss of bladder control; hoarse voice, drooping eyelids; vision changes, eye pain, severely dry or irritated eyes (your eyes may also be more sensitive to light); or chest pain or pressure, pain spreading to your jaw or shoulder, irregular heartbeats.

Warnings: The botulinum toxin contained in Jeuveau can spread to other body areas beyond where it was injected. This can cause serious life-threatening side effects. Call your doctor at once if you have a hoarse voice, drooping eyelids, vision problems, severe eye irritation, severe muscle weakness, loss of bladder control, or trouble breathing, talking, or swallowing.

Use during pregnancy or breastfeeding: Tell your doctor if you are pregnant or breastfeeding.