Oriahnn

Generic name: Elagolix, estradiol, and norethindrone

Drug class: Sex hormone combinations

Dosage forms: Tablet

Root of administration: Oral

Dose:0.5, 1, 300 mg

Mechanism of action: Oriahnn contains a combination of elagolix, estradiol, and norethindrone.

Drug usage cases: Oriahnn is a prescription medicine used to control heavy menstrual bleeding in adult women with uterine fibroids. Oriahnn is not for use in women who have entered menopause.

Drug contra indications: You should not use Oriahnn if you are allergic to elagolix, estradiol, or norethindrone, or if you have:

a history of heart attack, stroke; a blood clot in your heart, lungs, legs, or eyes; blood circulation problems; a heart valve disorder or heart rhythm problems; uncontrolled high blood pressure; problems caused by diabetes that affect your eyes, kidneys, nerves, or blood vessels; severe migraine headaches (with aura), especially if you are older than 35; gallbladder problems; a history of hormone-related cancer (such as cancer of the breast, uterus/cervix, or vagina); osteoporosis; or abnormal vaginal bleeding that has not been checked by a doctor. Taking Oriahnn can increase your risk of blood clots, stroke, or heart attack. You are even more at risk if you have high blood pressure, diabetes, high cholesterol, or if you are overweight. Smoking can greatly increase your risk of blood clots, stroke, or heart attack. You should not take Oriahnn if you smoke and are over 35 years old. Oriahnn may also cause bone loss, which may be partially permanent. It is not known if this could increase your risk of bone fracture. To make sure Oriahnn is safe for you, tell your doctor if you have ever had:

bone problems, including broken bones; depression, a mood disorder, or suicidal thoughts; or jaundice (yellowing of your skin or eyes) caused by pregnancy or birth control.

Side effects: Get emergency medical help if you have signs of an allergic reaction to Oriahnn: hives; difficult breathing; swelling of your face, lips, tongue, or throat. This medicine may increase your risk of heart attack, stroke, or blood clot. Stop using this medicine and seek medical attention right away if you have:

chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; swelling, pain, warmth, or redness in an arm or leg; sudden shortness of breath; sudden numbness, weakness, or severe headache; vision problems, bulging eyes; or trouble speaking. Call your doctor at once if you have:

high blood sugar – increased thirst, increased urination, dry mouth, fruity breath odor; any new or worsening mood symptoms – mood or behavior changes, depression, anxiety, thoughts about suicide or hurting yourself; or liver or gallbladder problems – loss of appetite, nausea, vomiting, stomach pain (upper right side), tiredness, bruising, swelling, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Oriahnn may cause hair loss that may be permanent.

Warnings: You should not use Oriahnn if you have: uncontrolled high blood pressure, heart disease, circulation problems (especially with diabetes), undiagnosed vaginal bleeding, liver disease, severe migraine headaches, osteoporosis, if you smoke and are over 35, or if you have ever had a heart attack, a stroke, a blood clot, or cancer of the breast, uterus/cervix, or vagina. Taking Oriahnn can increase your risk of blood clots, stroke, or heart attack. Your risk of these side effects is highest if you are older than 35 and you smoke, or if you have high cholesterol, diabetes, uncontrolled high blood pressure, or if you are overweight. Stop taking Oriahnn and seek medical attention right away if you have chest pain spreading to your jaw or shoulder, a sudden severe headache, problems with vision or speech, or swelling or pain in your leg.

Use during pregnancy or breastfeeding: Do not use Oriahnn if you are pregnant. Oriahnn is not a birth control medication and will not prevent pregnancy. You may need to have a negative pregnancy test before starting this treatment. Do not take Oriahnn if you are pregnant or trying to get pregnant. Oriahnn may increase your risk of miscarriage. Use effective birth control to prevent pregnancy while taking this medicine and for 28 days after your last dose. To prevent pregnancy while using Oriahnn, use a non-hormonal form of birth control: condom, diaphragm, cervical cap, or contraceptive sponge. Avoid using birth control pills, injections, implants, skin patches, and vaginal rings. Stop taking Oriahnn and call your doctor right away if you think you might be pregnant. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of elagolix, estradiol, and norethindrone on the baby. Oriahnn may change your menstrual periods (decreased or no bleeding), which could make it harder to know if you are pregnant. Watch for other signs of pregnancy such as breast tenderness, weight gain, and nausea.