Sevelamer

Generic name: Sevelamer

Drug class: Phosphate binders

Dosage forms: Powder for reconstitution, Tablet

Root of administration: Oral

Dose: Powder for reconstitution: carbonate 0.8, 2.4 g) Tablet: 400, 800 mg, carbonate 800 mg

Mechanism of action: Sevelamer is a phosphate binder. Sevelamer helps prevent hypocalcemia (low levels of calcium in the body) caused by elevated phosphorus.

Drug usage cases: Sevelamer is used to control phosphorus levels in people with chronic kidney disease who are on dialysis.

Drug contra indications: You should not take sevelamer if you are allergic to it, or if you have a bowel obstruction. To make sure sevelamer is safe for you, tell your doctor if you have:

trouble swallowing; severe constipation; a blockage in your intestines; slow digestion; a stomach or intestinal disorder; or if you have recently had stomach or intestinal surgery. Because sevelamer is not absorbed into the bloodstream, it is not expected to be harmful to a nursing baby. Sevelamer is not approved for use by anyone younger than 6 years old.

Side effects: Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Sevelamer may cause serious side effects. Stop using sevelamer and call your doctor at once if you have:

choking, or trouble swallowing; black, bloody, or tarry stools; severe constipation with stomach pain; or constipation that gets worse or does not clear up.

Warnings: You should not take sevelamer if you have a bowel obstruction.

Use during pregnancy or breastfeeding: It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Your dose needs may be different during pregnancy. Taking sevelamer while you are pregnant can lower your blood levels of certain vitamins or folic acid. Follow your doctor’s instructions about taking vitamins or mineral supplements during pregnancy.