Triloan II SUIK

Generic name: Triamcinolone Acetonide

Drug class: Corticosteroid

Dosage form: Injection, Suspension

Root of administration: Intra-articular; Intramuscular

Dose: 40 mg/mL

Mechanism of action: Triamcinolone acetonide is a synthetic corticosteroid that exerts anti-inflammatory and immunosuppressive effects by inhibiting the release of pro-inflammatory mediators and suppressing immune cell activity.

Drug usage cases:

• Management of allergic disorders
• Treatment of arthritis
• Management of gout
• Therapy for certain blood diseases
• Management of breathing problems
• Adjunctive treatment for certain cancers
• Management of eye diseases
• Therapy for intestinal disorders
• Management of collagen and skin diseases

Drug contra indications:

• Hypersensitivity to triamcinolone acetonide or any component of the formulation
• Active systemic fungal infections
• Administration of live vaccines during therapy
• Uncontrolled systemic infections
• Recent history of gastrointestinal perforation

Side effects:

• Injection site reactions (e.g., pain, swelling, redness)
• Elevated blood sugar levels
• Fluid retention leading to edema
• Increased appetite and weight gain
• Elevated blood pressure
• Osteoporosis with prolonged use
• Suppression of the hypothalamic-pituitary-adrenal (HPA) axis
• Gastrointestinal disturbances (e.g., nausea, vomiting)
• Psychiatric effects (e.g., mood swings, depression)
• Delayed wound healing

Warnings:

• Use with caution in patients with a history of peptic ulcer disease
• Monitor blood pressure regularly during therapy
• Assess bone density in patients on long-term therapy
• Gradual dose reduction is recommended to minimize HPA axis suppression
• Use cautiously in patients with a history of psychiatric disorders
• Monitor for signs of infection; may mask symptoms of existing infections
• Use cautiously in patients with a history of thromboembolic disorders
• Not recommended for use in pediatric patients for extended periods due to potential growth suppression

Use during pregnancy or breastfeeding:

Triamcinolone acetonide is classified as a Category C drug during pregnancy, indicating that risk to the fetus cannot be ruled out. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution is advised when administering this medication to nursing mothers, as it is not known whether triamcinolone acetonide is excreted in human milk. The decision to use this medication during breastfeeding should be made after careful consideration of the potential benefits and risks.