Yohimbine

Generic name: Yohimbine

Drug class: Impotence agents

Dosage forms: Tablet, Capsule, Liquid extract

Root of administration: Oral

Dose: 2.5,4, 5, 6 mg  

Mechanism of action: Yohimbine primarily works as an alpha-2 adrenergic receptor antagonist. It blocks the activity of alpha-2 receptors in the body, leading to increased release of norepinephrine and other neurotransmitters.

Drug usage cases: Yohimbine is used to increase peripheral blood flow. It is also used to dilate the pupil of the eye. Yohimbine is available only with your doctor’s prescription.

Drug contra indications: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Geriatric: Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of yohimbine in the elderly with use in other age groups, this medicine has been used in some elderly patients and has not been shown to cause different side effects or problems in older people than it does in younger adults. Interactions with Medicines: Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Side effects: Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor as soon as possible if any of the following side effects occur:

Less common: Fast heartbeat, increased blood pressure. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common: Dizziness, headache, irritability, nervousness or restlessness. Rare: Nausea and vomiting, skin flushing, sweating, tremor. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Warnings: Medical Conditions: Individuals with certain medical conditions should exercise caution or avoid using yohimbine. These conditions include heart disease, high blood pressure, kidney disease, liver disease, psychiatric disorders (such as anxiety or panic disorder), and bleeding disorders. Yohimbine can potentially worsen symptoms or interact with medications used to treat these conditions. Interactions with Medications: Yohimbine may interact with various medications, including those used for high blood pressure, depression, anxiety, and psychiatric disorders. Combining yohimbine with these medications can lead to increased heart rate, blood pressure, and other adverse effects. It’s important to consult with a healthcare professional or pharmacist to assess potential interactions before using yohimbine. Allergic Reactions: Allergic reactions to yohimbine are possible, although they are relatively rare. If you have a known allergy to yohimbine or any related substances, it’s important to avoid its use.

Use during pregnancy or breastfeeding: Pregnancy and Breastfeeding: Yohimbine is not recommended for use during pregnancy or while breastfeeding. There is limited information available on its safety during these periods, and potential risks to the fetus or infant are not well understood.